Funding

2023 [4 awarded]

Award 87

  • Title: DNAzyme discovery and optimization for high-yield DNA strand assembly
  • Names of applicants: Yingfu Li
  • Source agency: Seagate Technology LLC
  • Type: Contract
  • Amount: $64,508 [Total award; 1 year]

Award 86

  • Title: A colorimetric test for COVID-19
  • Names of applicants: Yingfu Li
  • Source agency: Innovation Factory
  • Type: Sophie Program
  • Amount: $100,000 [Total award; 2 years]

Award 85

  • Title: Development of a low-cost pen-side assay for rapid detection of African swine fever virus
  • Names of applicants: Yingfu Li, Leyla Soleymani
  • Source agency: Agriculture and Agri-Food Canada
  • Type: African Swine Fever Industry Preparedness Program
  • Amount: $469,680 [Total award; 2 years]

Award 84

  • Title: Discovery of serum biomarkers of neurodegenerative diseases with DNAzyme technology for diagnostic test for clinical use
  • Names of applicants: Yingfu Li, Mario Masellis
  • Source agency: Weston Brain Institute
  • Type: Transformational Research: Canada Alzheimer’s & Related Diseases 2020
  • Amount: $1,272,000 [Total award; 3 years]

2022 [4 awarded]

Award 83

  • Title: Rapid diagnostics for viral and bacterial pathogens
  • Names of applicants: Yingfu Li, Leyla Soleymani, Bruno Salena, Deborah Yamamura
  • Source agency: MITACS
  • Type: Accelerate
  • Amount: $1,655,000 [Total award; 3 years]

Award 82

  • Title: Pathogen diagnostic tests using functional nucleic acids
  • Names of applicants: Yingfu Li
  • Source agency: Zentek Limited
  • Type: Contract
  • Amount: $1,400,000 [Total award; 5 years]

Award 81

  • Title: Market translation of a rapid COVID-19 saliva test
  • Names of applicants: Yingfu Li, Leyla Soleymani
  • Source agency: NSERC
  • Type: |2| 2a
  • Amount: $348,440 [Total award; 2 years]

Award 80

  • Title: Development of aptamer-based biosensing platform technologies for rapid responses to future global pandemics
  • Names of applicants: Yingfu Li, Leyla Soleymani, 6 other co-applicants
  • Source agency: NSERC
  • Type: Alliance Missions
  • Amount: $994,186 [Total award; 2 years]

2021 [3 awarded]

Award 79

  • Title: A simple and cost-effective test for water-borne pathogen Legionella
  • Names of applicants: Yingfu Li, Carlos Filipe
  • Source agency: NSERC
  • Type: |2|
  • Amount: $123,000 [Total award; 1 year]

Award 78

  • Title: Development of a saliva and aptamer-based antigen test for variants of concern of SARS-CoV-2
  • Names of applicants: Yingfu Li, John Brennan, Leyla Soleymani, Bruno Salena, Carlos Filipe, Fred Capretta, Karen Mossman, Andrew McArthur, Deborah Yamamura, Cynthia Balion, Matthew Miller, Jonathan Gubbay
  • Source agency: CIHR
  • Type: Operating Grant: Emerging COVID-19 Research Gaps and Priorities Funding Opportunity [March 2021] 2021-04-15
  • Amount: $498,456 [Total award; 1 year]

Award 77

  • Title: UroPathogenMeter: A handheld electrical chip/reader technology for rapid urine analysis
  • Names of applicants: Yingfu Li, Leyla Soleymani, Todd Hoare
  • Source agency: NSERC
  • Type: |2|
  • Amount: $125,000 [Total award; 1 year]

2020 [9 awarded]

Award 76

  • Title: Developing a rapid point-of-care COVID-19 detection test with the potential to collect and transmit data
  • Names of applicants: Yingfu Li
  • Source agency: MITACS
  • Type: Accelerate
  • Amount: $45,000 [Total award; 1 year]

Award 75

  • Title: Expanding biosensing systems through synthetic functional deoxyribonucleic acids
  • Names of applicants: Yingfu Li
  • Source agency: NSERC
  • Type: Discovery
  • Amount: $525,000 [Total award; 5 years]

Award 74

  • Title: A simple and rapid point-of-care (POC) test for SARS-CoV-2
  • Names of applicants: Yingfu Li, Carlos Filipe, Cynthia Ballon, Matthew Miller
  • Source agency: NSERC
  • Type: NSERC Alliance COVID-19 grants
  • Amount: $50,000 [Total award; 1 year]

Award 73

  • Title: A Rapid High-Throughput Diagnostic Test for SARS-CoV-2
  • Names of applicants: John Brennan, Yingfu Li, Carlos Filipe, Fred Capretta, Karen Mossman, Cynthia Balion
  • Source agency: McMaster University
  • Type: Operating Grant: McMaster COVID-19 Research Fund
  • Amount: $150,000 [Total award; 1 year]

Award 72

  • Title: A rapid at-home test for SARS-CoV-2
  • Names of applicants: Yingfu Li, John Brennan, Carlos Filipe, Fred Capretta, Karen Mossman, Leyla Soleymani, Deborah Yamamura, Cynthia Ballon, Bruno Salena
  • Source agency: CIHR
  • Type: Operating Grant: COVID-19 Rapid Research Funding Opportunity – Diagnostics
  • Amount: $1,314,083 [Total award; 1 year]

Award 71

  • Title: A Portable DNA Species Detection Device for Conservation
  • Names of applicants: Carlos Filipe, Yingfu Li, Marco Musiani (U. Calgary)
  • Source agency: Alberta Innovates
  • Type: Land and Biodiversity Program
  • Amount: $180,000 [Total award; 4 years]

Award 70

  • Title: Preparation of Sentinel Wraps for Detection of Pathogens in Food Packages
  • Names of applicants: Tohid Didar, Yingfu Li
  • Source agency: MITACS
  • Type: Accelerate
  • Amount: $360,000 [Total award; 2 years]

Award 69

  • Title: Flexible food packaging wraps for real-time hands-free detection of bacteria
  • Names of applicants: Tohid Didar, Yingfu Li
  • Source agency: Toyota Tsushima Canada Inc.
  • Type: Contract
  • Amount: USD 300,000 [Total award; 2 years]

Award 68

  • Title: Unconventional biomarker identification for neurodegenerative disease amyotrophic lateral sclerosis
  • Names of applicants: Yingfu Li, John Turnbull, Bruno Salena, Yu Lu
  • Source agency: Government of Canada
  • Type: New Frontiers in Research Fund
  • Amount: $250,000 [Total award; 2 years]

2019 [2 awarded]

Award 67

  • Title: Paper-based DNA detection for conservation biology
  • Names of applicants: Carlos Filipe, Yingfu Li, Marco Musiani (U. Calgary)
  • Source agency: NSERC
  • Type: Collaborative Research and Development
  • Amount: $540,000 [Total award; 4 years]

Award 66

  • Title: Investigating novel biomarkers of pancreatic cancer
  • Names of applicants: Yingfu Li, Bruno Salena, Shawn Forbes
  • Source agency: Canadian Cancer Society
  • Type: Innovation Grants
  • Amount: $200,000 [Total award; 2 years]

2018 [1 awarded]

Award 65

  • Title: Programmed Molecules for Therapeutics, Sensing and Diagnostics (PROMOTE)
  • Names of applicants: Hanadi Sleiman, Shana Kelley, Nicolas Moitessier, Molly Shoichet, Chris Wilds, Gonzalo Cosa, Maureen Mckeague, Masad Damha, Yingfu Li
  • Source agency: NSERC/CIHR
  • Type: NSERC CREATE
  • Amount: $1,650,000 [Total award; 6 years]

2017 [2 awarded]

Award 64

  • Title: AgroPathogenMeter – developing a handheld platform for on-farm, rapid and inexpensive animal testing
  • Names of applicants: Leyla Soleymani, Yingfu Li, Todd Hoare
  • Source agency: NSERC
  • Type: Strategic Partnership Grants for Projects
  • Amount: $576,120 [Total award; 3 years]

Award 63

  • Title: E. coli litmus test for recreational water
  • Names of applicants: Yingfu Li
  • Source agency: Ontario Ministry of the Environment and Climate Change
  • Type: Contract
  • Amount: $60,000 [Total award; 2 years]

2016 [10 awarded]

Award 62

  • Title: Paper-based diagnostic device for colorectal cancer detection
  • Names of applicants: Yingfu Li, Bruno Salena, John Brennan, Carlos Filipe, Shawn Forbes, Paul Moayyedi, Kevin Zbuk
  • Source agency: CIHR/NSERC
  • Type: Collaborative Health Research Projects (CHRP)
  • Amount: $805,800 [Total award; 3 years]

Award 61

  • Title: Development of Chemical Sensors Based on Single-Walled Carbon Nanotube Conjugates with Aptamers
  • Names of applicants: Alex Adronov, Yingfu Li
  • Source agency: Faculty of Science, McMaster University
  • Type: Faculty of Science Research Fellows
  • Amount: $50,000 [Total award; 2 years]

Award 60

  • Title: E. coli litmus test for recreational water
  • Names of applicants: Yingfu Li
  • Source agency: Ontario Ministry of the Environment & Climate Change
  • Type: New technology development
  • Amount: $60,000 [Total award; 2 years]

Award 59

  • Title: Developing a strain-specific test for rapid diagnosis of Clostridium difficile
  • Names of applicants: Yingfu Li, Bruno Salena, Andrew McArthur, Christine Lee
  • Source agency: CIHR
  • Type: Antimicrobial Resistance: Point of Care Diagnostics in Human Health
  • Amount: $300,000 [Total award; 2 years]

Award 58

  • Title: A Novel Diagnostic Test for Early Detection of Amyotrophic Lateral Sclerosis
  • Names of applicants: Yingfu Li, Bruno Salena, John Turnbull
  • Source agency: Western Brain Institute
  • Type: RAPID RESPONSE
  • Amount: $150,000 [Total award; 18 months]

Award 57

  • Title: Legionella sensor
  • Names of applicants: Yingfu Li
  • Source agency: TGWT Clean Technology
  • Type: Contract
  • Amount: $15,000 [Total award; 3 years]

Award 56

  • Title: DNAPrint: a pathogen-tracking paper-sensor platform
  • Names of applicants: Yingfu Li, John Brennan, Carlos Filipe
  • Source agency: NSERC (Partners: TGWT Clean Technology; Cytodiagnostics; Molding & Bacteria Testing Laboratories)
  • Type: Strategic Partnership Project
  • Amount: $672,000 [Total award; 3 years]

Award 55

  • Title: Therapeutic aptamers
  • Names of applicants: Yingfu Li
  • Source agency: Vitrisa Therapeutics Inc.
  • Type: Research Contract
  • Amount: $135,500 [Total award; 1 year]

Award 54

  • Title: Developing a strain-specific test for rapid diagnosis of Clostridium difficile
  • Names of applicants: Yingfu Li, Andrew McArthur, Christine Lee, Bruno Salena
  • Source agency: CIHR
  • Type: Antimicrobial Resistance: Point of Care Diagnostics in Human Health
  • Amount: $10,000 [Total award; 1 year]

Award 53

  • Title: Therapeutic aptamers
  • Names of applicants: Yingfu Li
  • Source agency: Vitrisa Therapeutics Inc.
  • Type: Research Contract
  • Amount: $180,000 [Total award; 18 months]

2015 [3 awarded]

Award 52

  • Title: The Origins of Life Laboratory
  • Names of applicants: Maikel Rheinstaedter, Yingfu Li, Ralph Pudritz
  • Source agency: CFI John R. Evans Leaders Fund
  • Type: John R. Evans Leaders Fund
  • Amount: $1,016,496 [Total award; one time]

Award 51

  • Title: Expanding the function and utility of nucleic acids
  • Names of applicants: Yingfu Li
  • Source agency: NSERC
  • Type: Discovery Grant
  • Amount: $625,000 [Total award; 2015-2020]

Award 50

  • Title: Advanced Manufacturing of Printable Diagnostic Systems for Bioprocess Control and Personal Medicine
  • Names of applicants: John D. Brennan, Alfredo (Fred) Capretta, Carlos Filipe, Yingfu Li, Ravi Selvaganapathy, Leyla Soleymani
  • Source agency: Ontario Ministry of Research Innovation
  • Type: Ontario Research Fund – Research Excellence
  • Amount: $5,000,000 [Total award; 2015-2020]

2014 [5 awarded]

Award 49

  • Title: Developing bacterial litmus test kits
  • Names of applicants: Yingfu Li, Carlos Filipe
  • Source agency: NSERC Sentinel Bioactive Paper Network
  • Type: Technology Transfer
  • Amount: $184,000 [Total award; 2014-2015]

Award 48

  • Title: Aptamers for omega-3 fatty acids
  • Names of applicants: Yingfu Li
  • Source agency: NSERC
  • Type: Engage Plus
  • Amount: $25,000 [Total award; 2014]

Award 47

  • Title: Development of a Non-invasive Method for Early Colorectal Cancer Detection
  • Names of applicants: Yingfu Li, Bruno Salena
  • Source agency: Canadian Cancer Society
  • Type: Innovation Grant
  • Amount: $199,650 [Total award; 2014-2016]

Award 46

  • Title: Aptamers for omega-3 fatty acids
  • Names of applicants: Yingfu Li
  • Source agency: Pivotal Therapeutics Inc.
  • Type: Contract
  • Amount: $187,500 [Total award; 2014-2017]

Award 45

  • Title: Aptamers for omega-3 fatty acids
  • Names of applicants: Yingfu Li
  • Source agency: NSERC
  • Type: Engage
  • Amount: $25,000 [Total award; 2014]

2013 [2 awarded]

Award 44

  • Title: Development of Diagnostic Test Strips Incorporating Functional Nucleic Acids for Quantitative Detection of Disease Biomarkers
  • Names of applicants: John Brennan, Yingfu Li
  • Source agency: Ontario Centres of Excellence (OCE)
  • Type: Industry Sponsored Research
  • Amount: $558,000 [Total award; 2013-2015]

Award 43

  • Title: Development of Diagnostic Test Strips Incorporating Concatameric Aptamers for Quantitative Detection of C. difficile
  • Names of applicants: John Brennan, Yingfu Li
  • Source agency: NSERC
  • Type: CRD
  • Amount: $471,000 [Total award; 2013-2016]

2012 [2 awarded]

Award 42

  • Title: Toward a rational and novel therapy for Clostridium difficile infection
  • Names of applicants: Yingfu Li, Peter Kim, Christine Lee, Dylan Pillar, Donald Low
  • Source agency: NSERC/CIHR
  • Type: CHRP
  • Amount: $1,650,000 [Total award; 2011-2017]; $558,000 [Total award; 2012-2015]

Award 41

  • Title: Fluorescent indicator for Listeria
  • Names of applicants: Yingfu Li
  • Source agency: NSERC
  • Type: |2|
  • Amount: $125,000 [Total award; 2013]

2011 [1 awarded]

Award 40

  • Title: CREATE Biointerfaces Training Program
  • Names of applicants: John Brennan, Yingfu Li, 8 other co-applicants
  • Source agency: NSERC CREATE
  • Type: Training
  • Amount: $1,650,000 [Total award; 2011-2017]
  • PurposeThe project aims to provide unique training to graduate students, undergraduates and postdoctoral fellows in the development, characterization and application of bioactive and stealth biointerfaces for ophthalmic biomaterials and biosensor coatings.

2010 [4 awarded]

Award 39

  • Title: Sentinel Network – Phase II {Canadian Network for the Development and Use of Bioactive Paper)
  • Names of applicants: Robert Felton, Yingfu Li, 22 other co-applicants
  • Source agency: NSERC
  • Type: N/A
  • Amount: $7,500,000 [Total award; 2010-2015]

Award 38

  • Title: Aptamer sensors for food-borne pathogens
  • Names of applicants: Yingfu Li
  • Source agency: Canadian Food Inspection Agency
  • Type: N/A
  • Amount: $299,992 [Total award; 2010-2013]

Award 37

  • Title: Functional nucleic acids as catalysts and molecular recognition elements
  • Names of applicants: Yingfu Li
  • Source agency: NSERC
  • Type: Discovery Accelerator
  • Amount: $120,000 [Total award; 2010-2013]

Award 36

  • Title: Development of aptamer-based bioactive paper for food-borne bacterial pathogen detection
  • Names of applicants: Yingfu Li
  • Source agency: NSERC
  • Type: Forest Sector R&D Initiative – Extension
  • Amount: $165,500 [Total award; 2010-2011; 1 year]

2009 [8 awarded]

Award 35

  • Title: Catalytic DNA for protein sensing
  • Names of applicants: Yingfu Li, Tony Collins
  • Source agency: CIHR
  • Type: Research Tools
  • Amount: $292,815 [Total award; 2009-2012; 3 years]

Award 34

  • Title: Biointerfaces Institute
  • Names of applicants: John Brennan, John Brash, Michael Brook, Alfredo Capretta, Cecile Fradin, Raja Ghosh, Yingfu Li, Giuseppe Melacini, Robert Pelton, Heather Sheardown
  • Source agency: CFI
  • Type: N/A
  • Amount: $19,560,541 [Total award; one time]

Award 33

  • Title: Developing RNA-cleaving DNAzymes as Molecular Tools for Cancer Study and as Cancer Therapeutics
  • Names of applicants: Yingfu Li
  • Source agency: CIHR
  • Type: N/A
  • Amount: $616,690 [Total award; 2009-2014; 5 years]

Award 32

  • Title: Functional nucleic acids as catalysts and molecular recognition elements
  • Names of applicants: Yingfu Li
  • Source agency: NSERC
  • Type: N/A
  • Amount: $422,500 [Total award; 2009-2014]

Award 31

  • Title: Fluorescent DNAzymes as novel sensors for pathogenic bacteria
  • Names of applicants: Yingfu Li
  • Source agency: NSERC C4 POP
  • Type: Operating
  • Amount: $10,000 [Total award; 2009; 1 year]
  • Purpose: To develop signalling DNAzyme-based sensors for pathogenic bacteria

Award 30

  • Title: Developing RNA-cleaving DNAzymes as Molecular Tools for Cancer Study and as Cancer Therapeutics
  • Names of applicants: Yingfu Li
  • Source agency: CIHR
  • Type: N/A
  • Amount: $89,919 [Total award; 2009; 1 year]

Award 29

  • Title: Development of aptamer-based bioactive paper for food-borne bacterial pathogen detection
  • Names of applicants: Yingfu Li
  • Source agency: NSERC
  • Type: Forest Sector R&D Initiative
  • Amount: $165,500 [Total award; 2009-2010; 1 year]

Award 28

  • Title: Aptamers for bacterial toxins
  • Names of applicants: Yingfu Li
  • Source agency: Spectral Diagnostics
  • Type: N/A
  • Amount: $30,000 [Total award; 2009; 1 year]

2008 [2 awarded]

Award 27

  • Title: Development and Evaluation of RNA-cleaving DNAzymes that can specifically degrade mutant Huntingtin mRNAs
  • Names of applicants: Yingfu Li, Ray Truant
  • Source agency: CHDI Foundation
  • Type: N/A
  • Amount: $65,578 [Total award; 2008-2009]

Award 26

  • Title: Aptamers for bacterial toxins
  • Names of applicants: Yingfu Li
  • Source agency: Spectral Diagnostics
  • Type: N/A
  • Amount: $40,000 [Total award; 2008-2009; 1 year]

2007 [2 awarded]

Award 25

  • Title: Functional DNA Based Bioassays and Biosensors for the Detection of Pathogenic Bacteria in the Health Sector and Food Industry
  • Names of applicants: Yingfu Li, John Brennan, Chang-Qing Xu
  • Source agency: NSERC
  • Type: Strategic Project
  • Amount: $473,589 [Total award; 2007-2010]

Award 26

  • Title: Label-free Fibre Optic Biosensor for Bacterial (E. coli) Detection
  • Names of applicants: Chang-Qing Xu, Yingfu Li
  • Source agency: CPI
  • Type: Technology Exploitation and Networking Program
  • Amount: $30,000 [Total award; 2007-2008]

2006 [1 awarded]

Award 23

  • Title: Centre for Microbial Chemical Biology
  • Names of applicants: Gerard Wright, Christian Baron, John Brennan, Eric Brown, Alfredo Capretta, Yingfu Li, Brian McCarry, James McNulty, Justin Nodwell, Lesley Warren
  • Source agency: CFI (Canadian Foundation of Innovation) / Innovation Fund
  • Type: N/A
  • Amount: $19,560,070 [Total award; 2006]

2005 [1 awarded]

Award 22

  • Title: Canadian Network for the Development and Use of Bioactive Paper
  • Names of applicants: Robert Felton, Yingfu Li, 22 other co-applicants
  • Source agency: NSERC
  • Type: N/A
  • Amount: $7,500,000 [Total award; 2005-2010]

2004 [5 awarded]

Award 21

  • Title: Mass Spectrometer-based Flow Cytometer, Methods and Applications
  • Names of applicants: John Dick, Scott Tanner, Yingfu Li, Mark Minden
  • Source agency: Genome Canada
  • Type: N/A
  • Amount: $8,462,065 [Total award; 2004-2007]

Award 20

  • Title: DNA aptamers and DNA enzymes as molecular recognition elements
  • Names of applicants: Yingfu Li
  • Source agency: NSERC
  • Type: Discovery Program
  • Amount: $196,700 [Total award; 2004-2009]

Award 19

  • Title: Developing aptamers as antidotes for antithrombotic drugs
  • Names of applicants: Yingfu Li, Jeff Weitz
  • Source agency: McMaster University
  • Type: N/A
  • Amount: $85,000 [Total award; 2004-2005]

Award 18

  • Title: Studying DNA aptamers as bioanalytical tools
  • Names of applicants: Yingfu Li
  • Source agency: Government of Ontario
  • Type: Premier’s Research Excellence Award Program
  • Amount: $150,000 [Total award; 2004-2009]

Award 17

  • Title: Centre for Functional Genomics and Chemical Genetics
  • Names of applicants: David W. Andrews, Eric Brown, Cecile Fradin, John Hassell, Yingfu Li, Justin Nodwell, Ray Truant, Jeff Weitz, Gerard Wright
  • Source agency: CFI (Canada Foundation of Innovation) / Innovation Fund
  • Type: N/A
  • Amount: $10,956,883 [Total award; 2004-2005]