Ryan Amini

Ryan is an undergraduate student in the Li Lab, where he is completing his fourth-year senior thesis. His project focuses on the characterization of DNA aptamers that bind to the SARS-CoV-2 spike protein. Under the guidance of Dr. Li, Ryan has achieved an NSERC CREATE PROMOTE Scholarship and an NSERC USRA.
Outside of the lab, Ryan enjoys playing/watching basketball!

Functional nucleic acids, pathogen diagnostics.

Publications:

Li J, Zhang Z, Liu R, Amini R, Salena B, Li Y. (2022). Discovery and Translation of Functional Nucleic Acids for Clinically Diagnosing Infectious Diseases: Opportunities and Challenges. TRAC. doi: 10.1016/j.trac.2022.116886

Li J, Zhang Z, Gu J, Amini R, Mansfield A, Xia J, White D, Stacey H, Ang J, Panesar G, Capretta A, Filipe C, Mossman K, Salena B, Gubbay J, Balion C, Soleymani L, Miller M, Yamamura D, Brennan J, Li Y. (2022). Three on Three: Universal and High-Affinity Molecular Recognition of the Symmetric Homotrimeric Spike Protein of SARS- CoV-2 with a Symmetric Homotrimeric Aptamer. J. Am. Chem. Soc. doi: 10.1021/jacs.2c09870

Amini R, Zhang Z, Li J, Gu J, Brennan J, Li Y. (2022). Aptamers for SARS-CoV-2: Isolation, Characterization, Diagnostic and Therapeutic Developments. Anal Sens. 2(5): e202200012 doi: 10.1002/anse.202200012

Li J, Zhang Z, Amini R, Li Y. (2022). One Solution for All: Searching for Universal Aptamers for Constantly Mutating Spike Proteins of SARS-CoV-2. ChemMedChem. 17(13): e2022001166 doi: 10.1002/cmdc.202200166 

Zhang Z, Li J, Gu J, Amini R, Stacey H, Ang J, White D, Filipe C, Mossman K, Miller M, Salena B, Yamamura Y, Sen P, Soleymani L, Brennan J, Li Y. (2022). A Universal DNA Aptamer that Recognizes Spike Proteins of Diverse SARS- CoV-2 Variants of Concern. Chemistry. 28(15): e202200078 doi: 10.1002/chem.202200078

Chang T, He S, Amini R, Li Y. (2021). Functional Nucleic Acids Under Unusual Conditions. ChemBioChem. 22(14): 2368-2383 doi: 10.1002/cbic.202100087