Dingran Chang


Graduate Student

Ph.D. Biochemistry & Biomedical Sciences, McMaster University, anticipated 2018

B.Sc. Biopharmacy, China Pharmaceutical University, 2012

Department of Biochemistry and Biomedical Sciences
McMaster University
Health Science Centre, Room 4H32
1280 Main Street West
Hamilton, Ontario, L8S 4K1

icon_phone 905.525.9140 ext.28813
icon_fax 905.522.9033
icon_mail changd3@mcmaster.ca


Brief Biography:

After completing his undergraduate degree at China Pharmaceutical University, Dingran Chang decided to come to Canada and continue his graduate studies at McMaster University.
In his spare time, Dingran enjoys running, cycling and camping. Recently, he is interested in learning to dance salsa. 

Research Interests:

My current research interests are in biosensor development.


Liu, M., Chang, D., Li, Y. Discovery and Biosensing Applications of Diverse RNA-Cleaving DNAzymes. Acc. Chem. Res. 2017, doi:10.1021/acs.accounts.7b00262

Chang, D.; Tram, K.; Li, B.; Feng, Q.; Shen, Z.; Lee, H.C., Salena, B.J., Li, Y. Detection of DNA amplicons of polymerase chain reaction using litmus test. Scientific Reports 2017, 7, 3110.

Manochehry, S.; Liu, M.; Chang, D.; Li, Y. Optical biosensors utilizing Graphene and functional DNA molecules. Journal of Materials Research 2017, 1–11. doi:10.1557/jmr.2017.103

Liu, M., Zhang, Q., Chang, D., Gu, J., Brennan, J. D., & Li, Y. A DNAzyme Feedback Amplification Strategy for Biosensing. Angewandte Chemie International Edition 2017. https://doi.org/10.1002/anie.201700054

Zhang, A.; Chang, D.; Zhang, Z.; Li, F.; Li, W.; Wang, X.; Li, Y.; Hua, Q. In vitro selection of DNA aptamers that binds geniposide. Molecules 2017, 22(3), 383

Chang, D.; Zakaria, S.; Deng, M.; Allen, N.; Tram, K.; Li, Y. Integrating deoxyribozymes into colorimetric sensing platforms. Sensors 2016, 16, 2061.

Tram, K.; Manochehry, S.; Feng, Q.; Chang, D.; Salena, B.J.; Li, Y. Colorimetric detection of bacteria using litmus test. Journal of visualized experiments: JoVE 2016.

Zhang, W.; Feng, Q.; Chang, D.; Tram, K.; Li, Y. In vitro selection of RNA-cleaving dnazymes for bacterial detection. Methods 2016, 106, 66-75.

Shen, Z.; Wu, Z.; Chang, D.; Zhang, W.; Tram, K.; Lee, C.; Kim, P.; Salena, B.J.; Li, Y. A catalytic DNA activated by a specific strain of bacterial pathogen. Angewandte Chemie International Edition 2016, 55, 2431-2434. (Co-first author)

Liu, M.; Zhang, W.; Chang, D.; Zhang, Q.; Brennan, J.D.; Li, Y. Integrating graphene oxide, functional DNA and nucleic-acid-manipulating strategies for amplified biosensing. TrAC Trends in Analytical Chemistry 2015, 74, 120-129

Book Chapters:

Rachel, G.; Kha, T.; Sepehr, M.; Dingran, C.; Yingfu, L. Selection and application of catalytically active oligonucleotides. In Aptamers, Pan Stanford: 2016; pp 75-112.