Welcome to Giulia Core

The Li Lab welcome our newest member, Giulia Core, who will be joining us as a visiting Ph.D. student from the University of Glasgow. She will be working on molecular diagnostic technologies.

DNA Aptamers for SARS-CoV-2

The Li Lab and our collaborators from across the McMaster community have published our first report on our novel aptamers for COVID19! The lab has refocused our efforts over the past year to address pressing COVID19 problems and we’re excited to finally be sharing our work. Read more about our work at Pubmed.

NSERC & L’Oréal-UNESCO Women in Science and IUPAC Young Chemist

Li Lab postdoctoral fellow Erin McConnell has been awarded the NSERC & L’Oréal-UNESCO Women in Science Supplement. Congratulations to Erin for her fantastic work as a scientist and as a role model for young scientists around the world.

Explore the following links to learn more about Erin’s work and the work of the other great researchers recently recognized.

Canadian Awarding ceremony of the L’Oréal-UNESCO For Women in Science fellowships

NSERC and L’Oréal-UNESCO For Women in Science Supplement

L’Oréal-UNESCO For Women in Science 2018: Erin McConnell

IUPAC Young Chemist

https://iupac.org/100/pt-of-chemist/#erin-mcconnell-he

A DNAzyme Feedback Amplification Strategy for Biosensing

Take a look at this recent publication from the Li Lab in Angewandte Chemie International Edition. In this paper, we explore a novel signal amplification strategy termed DNAzyme feedback amplification (DFA). This method takes advantage of rolling circle amplification and RNA-cleaving DNAzymes for biosensing applications, with sensitivity improvements of 3-6 orders of magnitude when compared to conventional methods. -Suraj

Detection of DNA Amplicons of Polymerase Chain Reaction Using Litmus Test

Checkout this recent paper from the Li Lab in Scientific Reports, “Detection of DNA Amplicons of Polymerase Chain Reaction Using Litmus Test.” Here we report on a novel DNA detection method that combines the advantages of the polymerase chain reaction with the simplicity of a litmus test. The diagnostic capabilities of the platform is demonstrated using clinically validated stool samples from C.difficile infected patients. -Suraj