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Jim Gu

Graduate Student

M.Sc. Biochemistry, McMaster University, anticipated 2011

B.Sc. Biochemistry, McMaster University, 2008

 

Department of Biochemistry and Biomedical Sciences
McMaster University
Health Science Centre, Room 4H31B
1280 Main Street West
Hamilton, Ontario, L8S 4K1

905.525.9140 ext.22757 | ext.28813
905.522.9033
guj4@mcmaster.ca

Brief Biography:

Jim started research work in the Li lab as an undergraduate working with Ken Schlosser on RNA cleaving DNAzymes doing characterization and selection experiments. He continued his undergraduate studies in the lab working on in vitro selection and bacterial high throughput screening projects for small RNAs. Jim began his Masters work with the lab in 2008 continuing his bacterial screening project and later shifting to in vivo selection for DNA aptamers against cancer cell lines.

"The greatest scientific advance of the last 12 years was…RNA interference"

Research Interests:

My current research interests are in cell selection.


Publications:


Journal Articles:
2.
Mok, W. W. K., Navani, N. K. Barker, C., Sawchyn, B. L., Gu, J., Pathania, R., Zhu, R. D., Brown, E. D. & Li, Y. (2009). Identification of a toxic peptide through bidirectional expression of small RNAs. ChemBioChem. 10, 238-241. [link]
1.
Schlosser, K., Gu, J., Lam, J. C. F. & Li, Y. (2008). In vitro selection of small RNA-cleaving deoxyribozymes that cleave pyrimidine-pyrimidine junctions. Nucleic Acids Res. 36, 4768- 4777. [link]