The holiday season was busy time for the lab. As snow piled up outside, the Li lab decided to spice up the winter with the perfect combination of mystery and excitement – a Secret Santa party! Although Dr.Li offered to give the best gift of all time (designing a figure for any upcoming journal publication) unfortunately he was not able to attend the party due to a conference in Singapore. As the Li lab spends a lot of time with each other in the lab on daily basis, we saw each others’ inner playfulness reflected in our gifts. Kha received a colour-changing mug from Jim in which showed a molecular beacon figure when containing hot water.Some of us received mini Lego sets, stuffed animals and even a kitten book for bed time. Most of people did a great job disguising themselves and really made it challenging to guess the identity of their secret Santas. The party ended in everyone’s laughter and a group photo. We thank Dora and Qian for their enthusiasm to organize and host the event and we hope all our readers enjoyed a great holiday and a Christmas full of laughter!